Smoking cannabis and consuming infused cannabis edibles provide two totally different effects. This is especially true when it comes to the intensity of the effects. If you have consumed cannabis through both infused edible products and inhalation methods such as smoking or vaping, this is probably a truth that you know firsthand.
Have you ever stopped to ask yourself why? If so, the answers you seek are in the content below!
The reason for this in simple terms is cannabis is absorbed and metabolized differently with these two consumption methods. When you smoke cannabis, cannabinoids are absorbed into the bloodstream and reach cannabinoid receptors by way of the bloodstream. When you consume cannabis through infused edibles, cannabinoids are broken down by saliva followed by the stomach and liver before reaching the bloodstream and travelling throughout the body.
The Inhalation Breakdown
When consuming edibles, the effects that consumers and patients experience is different primarily because the underlying cannabinoid responsible for the effect is actually different, contrary to what many may think.
When you smoke or vape cannabis, THC or Delta-9-THC is quickly absorbed through the alveoli in the lungs and then goes directly to your bloodstream on the way to their final destination being cannabinoid receptors.
The Edible Breakdown
When you consume an edible however, Delta-9-THC is broken down by the saliva in your mouth upon consumption, and further broken down and metabolized by your stomach and liver. During this process Delta-9-THC or THC as many know it actually changes to 11-hydroxy-THC.
This form of THC is thought to be much more potent than Delta-9-THC. 11-Hydroxy-THC is also much more water soluble than Delta-9-THC which means that once it hits the bloodstream it can carry through the blood much easier
The Supporting Research
Researchers at the Lilly Laboratory for Clinical Research performed a study in which they injected 9 subjects with 1mg of 11-hydroxy-THC and with THC at a later time. The subjects were asked to rate the effects on a range scale of 0-10. Here is what researchers had to say about the results.
All subjects reported a maximum psychologic high within 2-3 min after the intravenous administration of 11-OH-??-THC that was more intense than that previously experienced after smoking marihuana.
After the intravenous administration of 11-OH-??-THC, there were pronounced psychologic and pharmacologic effects marked tachycardia, an intense psychologic high, and considerable symptoms were produced.
Unfortunately, this is all science has to offer us regarding the potency of 11-hydroxy-THC but its enough to gather a good conclusion that edibles indeed provide more potent effects than Delta-9-THC.
While edibles may take up to 2 hours before they allow you to feel their effects, they are well worth the wait. It is easy to see how many find microdosing with edibles to bring them the perfect balance of relief throughout the day and night. Its also easy to see how the cannabis-infused edibles market is expected to reach a value of almost $20 billion by 2024.
Are you a fan of cannabis edibles or do you prefer to smoke a joint or enjoy a few puffs from a vape pen? Look us up on social media @Roottie.com and let us know in a comment or shoutout to us in a post! We love to learn more about the preferences and experiences of our readers! Until next time, stay lifted and gifted buds!